The discovery of a novel series of potential ERRα inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo

• Main Authors: Zhipei Gao (Author), Tianxiao Wang (Author), Rui Li (Author), Yongli Du (Author), Han Lv (Author), Liudi Zhang (Author), Haifei Chen (Author), Xiaojin Shi (Author), Qunyi Li (Author), Jingkang Shen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oestrogen related receptor α participated in the regulation of oxidative metabolism and mitochondrial biogenesis, and was overexpressed in many cancers including triple-negative breast cancer. A set of new ERRα inverse agonists based on p-nitrobenzenesulfonamide template were discovered and compound...