Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts.

• Main Authors: Germain Chevignon (Author), Vincent Foray (Author), Mercedes Maria Pérez-Jiménez (Author), Silvia Libro (Author), Matthew Chung (Author), Jeremy M Foster (Author), Frédéric Landmann (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brugia malayi is a human filarial nematode responsible for elephantiasis, a debilitating condition that is part of a broader spectrum of diseases called filariasis, including lymphatic filariasis and river blindness. Almost all filarial nematode species infecting humans live in mutualism with Wolbac...