Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery

• Main Authors: Min-Jeong Lee (Author), Ji-Yoon Kim (Author), Paul Kim (Author), In-Seo Lee (Author), Medard E. Mswahili (Author), Young-Seob Jeong (Author), Guang J. Choi (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs). It is administered as a fumarate salt for the treatment of acid-related diseases, including reflux esophagitis, gastric ulcer, and duodenal ulcer, and for er...