Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery

• Hauptverfasser: Min-Jeong Lee (Verfasst von), Ji-Yoon Kim (Verfasst von), Paul Kim (Verfasst von), In-Seo Lee (Verfasst von), Medard E. Mswahili (Verfasst von), Young-Seob Jeong (Verfasst von), Guang J. Choi (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs). It is administered as a fumarate salt for the treatment of acid-related diseases, including reflux esophagitis, gastric ulcer, and duodenal ulcer, and for er...