Akkermansia Muciniphila Potentiates the Antitumor Efficacy of FOLFOX in Colon Cancer

• Main Authors: Xiaoying Hou (Author), Pei Zhang (Author), Hongzhi Du (Author), Weihua Chu (Author), Ruiqi Sun (Author), Siyuan Qin (Author), Yuan Tian (Author), Zunjian Zhang (Author), Fengguo Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

FOLFOX (oxaliplatin, fluorouracil and calcium folinate) is the first-line chemotherapy regimen for colon cancer therapy in the clinic. It provides superior efficacy than oxaliplatin alone, but the underlying mechanism remains unclear. In the present study, pharmacomicrobiomics integrated with metabo...