Clozapine re-challenge and initiation following neutropenia: a review and case series of 14 patients in a high-secure forensic hospital

• Egile Nagusiak: Edward Silva (Egilea), Melanie Higgins (Egilea), Barbara Hammer (Egilea), Paul Stephenson (Egilea)
• Formatua: Liburua
• Argitaratua: SAGE Publishing, 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Clozapine remains the most effective intervention for treatment resistant schizophrenia; however, its use is prohibited following neutropenias. We review neutrophil biology as applied to clozapine and describe the strategies to initiate clozapine following neutropenia used in a case serie...