Tetramisole is a new IK1 channel agonist and exerts IK1‐dependent cardioprotective effects in rats

• मुख्य लेखकों: Qinghua Liu (लेखक), Jiaxing Sun (लेखक), Yangdou Dong (लेखक), Pan Li (लेखक), Jin Wang (लेखक), Yulan Wang (लेखक), Yanwu Xu (लेखक), Xinrui Tian (लेखक), Bowei Wu (लेखक), Peifeng He (लेखक), Qi Yu (लेखक), Xuechun Lu (लेखक), Jimin Cao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Cardiac ischemia, hypoxia, arrhythmias, and heart failure share the common electrophysiological changes featured by the elevation of intracellular Ca2+ (Ca2+ overload) and inhibition of the inward rectifier potassium (IK1) channel. IK1 channel agonists have been considered a new type of ant...