Emotional behavior and brain anatomy of the mdx52 mouse model of Duchenne muscular dystrophy

• Main Authors: Amel Saoudi (Author), Faouzi Zarrouki (Author), Catherine Sebrié (Author), Charlotte Izabelle (Author), Aurélie Goyenvalle (Author), Cyrille Vaillend (Author)
• Format: Book
• Published: The Company of Biologists, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The exon-52-deleted mdx52 mouse is a critical model of Duchenne muscular dystrophy (DMD), as it features a deletion in a hotspot region of the DMD gene, frequently mutated in patients. Deletion of exon 52 impedes expression of several brain dystrophins (Dp427, Dp260 and Dp140), thus providing a key...