The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability

• Asıl Yazarlar: Limei Wang (Yazar), Veronika Palme (Yazar), Nicole Schilcher (Yazar), Angela Ladurner (Yazar), Elke H. Heiss (Yazar), Herbert Stangl (Yazar), Rudolf Bauer (Yazar), Verena M. Dirsch (Yazar), Atanas G. Atanasov (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We report increased cholesterol efflux from macrophages in the presence of falcarindiol, an important dietary constituent present in commonly used vegetables and medicinal plants. Falcarindiol (3-20 μM) increased cholesterol efflux from THP-1-derived macrophages. Western blot analysis showed an incr...