Mycobacterium tuberculosis Multidrug-Resistant Strain M Induces Low IL-8 and Inhibits TNF-α Secretion by Bronchial Epithelial Cells Altering Neutrophil Effector Functions

• Main Authors: Denise Kviatcovsky (Author), Leonardo Rivadeneyra (Author), Luciana Balboa (Author), Noemí Yokobori (Author), Beatriz López (Author), Viviana Ritacco (Author), Mirta Schattner (Author), María del Carmen Sasiain (Author), Silvia de la Barrera (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

M strain, the most prevalent multidrug-resistant strain of Mycobacterium tuberculosis (Mtb) in Argentina, has mounted mechanisms to evade innate immune response. The role of human bronchial epithelium in Mtb infection remains unknown as well as its crosstalk with neutrophils (PMN). In this work, we...