Imidazopyridine-Based Thiazole Derivatives as Potential Antidiabetic Agents: Synthesis, In Vitro Bioactivity, and In Silico Molecular Modeling Approach

• Main Authors: Rafaqat Hussain (Author), Wajid Rehman (Author), Shoaib Khan (Author), Aneela Maalik (Author), Mohamed Hefnawy (Author), Ashwag S. Alanazi (Author), Yousaf Khan (Author), Liaqat Rasheed (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A new series of thiazole derivatives (<b>4a-p</b>) incorporating imidazopyridine moiety was synthesized and assessed for their in vitro potential α-glucosidase potency using acarbose as a reference drug. The obtained results suggested that compounds <b>4a</b> (docking score =...