Genetically modifying the insect gut microbiota to control Chagas disease vectors through systemic RNAi.

• Main Authors: Mabel L Taracena (Author), Pedro L Oliveira (Author), Olivia Almendares (Author), Claudia Umaña (Author), Carl Lowenberger (Author), Ellen M Dotson (Author), Gabriela O Paiva-Silva (Author), Pamela M Pennington (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Technologies based on RNA interference may be used for insect control. Sustainable strategies are needed to control vectors of Chagas disease such as Rhodnius prolixus. The insect microbiota can be modified to deliver molecules to the gut. Here, Escherichia coli HT115(DE3) expressing dsRNA for the R...