Sulphonamide inhibition profile of Staphylococcus aureus β-carbonic anhydrase

• Main Authors: Linda J. Urbanski (Author), Silvia Bua (Author), Andrea Angeli (Author), Marianne Kuuslahti (Author), Vesa. P. Hytönen (Author), Claudiu T. Supuran (Author), Seppo Parkkila (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This paper presents the production and kinetic and inhibitory characterisation of β-carbonic anhydrase from the opportunistic bacterium Staphylococcus aureus (SauBCA). From the eight different carbonic anhydrase (CA) families known to date, humans have only the α-form, whereas many clinically releva...