Safety and Efficacy of Ketamine Versus Ketamine-Fentanyl-Dexmedetomidine Combination for Anesthesia and Analgesia in Rats

• Main Authors: Chunzhu Li (Author), Jiali Peng (Author), Rong Hu (Author), Jia Yan (Author), Yu Sun (Author), Lei Zhang (Author), Wenbin Liu (Author), Hong Jiang (Author)
• Format: Book
• Published: SAGE Publishing, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ketamine (KET), a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, is most frequently used as an anesthetic, analgesic, and sedative drug in pediatric clinical practices. However, the adverse effects of KET administration such as psychotic episodes limited the use of KET. The aim of t...