Importance of Stability Analysis When Using Nonlinear Semimechanistic Models to Describe Drug‐Induced Hematotoxicity

Stability analysis, often overlooked in pharmacometrics, is essential to explore dynamical systems. The model developed by Friberg et al.1 to describe drug‐induced hematotoxicity is widely used to support decisions across drug development, and parameter values are often identified from observed bloo...

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Bibliographic Details
Main Authors: Chiara Fornari (Author), Carmen Pin (Author), James W.T. Yates (Author), Jerome T. Mettetal (Author), Teresa A. Collins (Author)
Format: Book
Published: Wiley, 2020-09-01T00:00:00Z.
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