Preclinical Evaluation of Dimethyl Itaconate Against Hepatocellular Carcinoma via Activation of the e/iNOS-Mediated NF-κB-Dependent Apoptotic Pathway

• Main Authors: Anurag Kumar Gautam (Author), Pranesh Kumar (Author), Ritu Raj (Author), Dinesh Kumar (Author), Bolay Bhattacharya (Author), P.S. Rajinikanth (Author), Kumarappan Chidambaram (Author), Tarun Mahata (Author), Biswanath Maity (Author), Sudipta Saha (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is one of the most common tumors affecting a large population worldwide, with the fifth and seventh greatest mortality rates among men and women, respectively, and the third prime cause of mortality among cancer victims. Dimethyl itaconate (DI) has been reported to be...