Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice

Enhanced insulin signaling in density-enhanced phosphatase-1 (DEP-1) knockout mice

Objective: Insulin resistance can be triggered by enhanced dephosphorylation of the insulin receptor or downstream components in the insulin signaling cascade through protein tyrosine phosphatases (PTPs). Downregulating density-enhanced phosphatase-1 (DEP-1) resulted in an improved metabolic status...

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Main Authors: Janine Krüger (Author), Sebastian Brachs (Author), Manuela Trappiel (Author), Ulrich Kintscher (Author), Heike Meyborg (Author), Ernst Wellnhofer (Author), Christa Thöne-Reineke (Author), Philipp Stawowy (Author), Arne Östman (Author), Andreas L. Birkenfeld (Author), Frank D. Böhmer (Author), Kai Kappert (Author)
Format: Book
Published: Elsevier, 2015-04-01T00:00:00Z.
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3rd Floor Main Library

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