Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies

• Glavni autori: Eleonora eSavio Galimberti (Autor), Michael eGollob (Autor), Dawood eDarbar (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2012-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Voltage-gated sodium channels (VGSC) are multi-molecular protein complexes expressed in both excitable and non-excitable cells. They are primarily formed by a pore-forming multi-spanning integral membrane glycoprotein (α-subunit) that can be associated with one or more regulatory β-subunits. The lat...