Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies

• Hauptverfasser: Eleonora eSavio Galimberti (Verfasst von), Michael eGollob (Verfasst von), Dawood eDarbar (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2012-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Voltage-gated sodium channels (VGSC) are multi-molecular protein complexes expressed in both excitable and non-excitable cells. They are primarily formed by a pore-forming multi-spanning integral membrane glycoprotein (α-subunit) that can be associated with one or more regulatory β-subunits. The lat...