Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies

• Auteurs principaux: Eleonora eSavio Galimberti (Auteur), Michael eGollob (Auteur), Dawood eDarbar (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2012-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Voltage-gated sodium channels (VGSC) are multi-molecular protein complexes expressed in both excitable and non-excitable cells. They are primarily formed by a pore-forming multi-spanning integral membrane glycoprotein (α-subunit) that can be associated with one or more regulatory β-subunits. The lat...