ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons

• Main Authors: Fierro Leonardo (Author), Immke David C (Author), Molliver Derek C (Author), Paré Michel (Author), Rice Frank L (Author), McCleskey Edwin W (Author)
• Format: Book
• Published: SAGE Publishing, 2005-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>ASIC3, the most sensitive of the acid-sensing ion channels, depolarizes certain rat sensory neurons when lactic acid appears in the extracellular medium. Two functions have been proposed for it: 1) ASIC3 might trigger ischemic pain i...