The emerging role of tranexamic acid and its principal target, plasminogen, in skeletal health

• Main Authors: Weixin Xie (Author), Antonia Donat (Author), Shan Jiang (Author), Anke Baranowsky (Author), Johannes Keller (Author)
• Format: Bog
• Udgivet: Elsevier, 2024-07-01T00:00:00Z.
• Fag: article
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The worldwide burden of skeletal diseases such as osteoporosis, degenerative joint disease and impaired fracture healing is steadily increasing. Tranexamic acid (TXA), a plasminogen inhibitor and anti-fibrinolytic agent, is used to reduce bleeding with high effectiveness and safety in major surgical...