Internalization and Transport of PEGylated Lipid-Based Mixed Micelles across Caco-2 Cells Mediated by Scavenger Receptor B1

• Glavni autori: Xiangjie Su (Autor), Mercedes Ramírez-Escudero (Autor), Feilong Sun (Autor), Joep B. van den Dikkenberg (Autor), Mies J. van Steenbergen (Autor), Roland J. Pieters (Autor), Bert J. C. Janssen (Autor), Peter M. van Hasselt (Autor), Wim E. Hennink (Autor), Cornelus F. van Nostrum (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The aim of this study was to get insight into the internalization and transport of PEGylat-ed mixed micelles loaded by vitamin K, as mediated by Scavenger Receptor B1 (SR-B1) that is abundantly expressed by intestinal epithelium cells as well as by differentiated Caco-2 cells. Inhibition of SR-B1 re...