A non-proliferative role of pyrimidine metabolism in cancer
Background: Nucleotide metabolism is a critical pathway that generates purine and pyrimidine molecules for DNA replication, RNA synthesis, and cellular bioenergetics. Increased nucleotide metabolism supports uncontrolled growth of tumors and is a hallmark of cancer. Agents inhibiting synthesis and i...
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Elsevier,
2020-05-01T00:00:00Z.
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