Asian flush gene variant increases mild cognitive impairment risk: a cross-sectional study of the Yoshinogari Brain MRI Checkup Cohort

• Main Authors: Mikiko Tokiya (Author), Manabu Hashimoto (Author), Kenji Fukuda (Author), Kazuhiro Kawamoto (Author), Chiho Akao (Author), Mariko Tsuji (Author), Yusuke Yakushiji (Author), Haruki Koike (Author), Akiko Matsumoto (Author)
• Format: Book
• Published: Komiyama Printing Co. Ltd, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The East Asian-specific genetic diversity, the rs671 variant of aldehyde dehydrogenase 2, causes the "Asian flush" phenomenon following alcohol consumption, resulting in an alcohol avoidance phenotype. The variant is suggested as a risk factor for Alzheimer's disease; howe...