Differential immunoglobulin and complement levels in leprosy prior to development of reversal reaction and erythema nodosum leprosum.

• Main Authors: Francianne M Amorim (Author), Maurício L Nobre (Author), Larissa S Nascimento (Author), Alesson M Miranda (Author), Glória R G Monteiro (Author), Francisco P Freire-Neto (Author), Maria do Carmo Palmeira Queiroz (Author), José W Queiroz (Author), Malcolm S Duthie (Author), Marcos R Costa (Author), Steven G Reed (Author), Warren D Johnson (Author), Kathryn M Dupnik (Author), Selma M B Jeronimo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Leprosy is a treatable infectious disease caused by Mycobacterium leprae. However, there is additional morbidity from leprosy-associated pathologic immune reactions, reversal reaction (RR) and erythema nodosum leprosum (ENL), which occur in 1 in 3 people with leprosy, even with effective...