Comparative Bioavailability and Pharmacokinetics Between the Solid Form of Metformin vs a Novel Liquid Extemporaneous Formulation in Children

• Main Authors: Radamés Alemón-Medina (Author), Nelly Altamirano-Bustamante (Author), Gustavo Lugo-Goytia (Author), Raquel García-Álvarez (Author), Liliana Rivera-Espinosa (Author), Luz María Torres-Espíndola (Author), Juan Luis Chávez-Pacheco (Author), Hugo Juárez-Olguín (Author), Josefina Gómez-Garduño (Author), Carmen Flores-Pérez (Author), Paola Gabriela Fernández-Pérez (Author)
• Format: Book
• Published: SAGE Publishing, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin pharmacokinetics in a liquid extemporaneous formulation from commercial tablets was determined in paediatric patients. A randomized, transversal clinical trial was conducted in 34 children and adolescents between 7 and 17 years of age. 17 children were randomized to take metformin in the l...