Adenoviral-mediated correction of methylmalonyl-CoA mutase deficiency in murine fibroblasts and human hepatocytes

Adenoviral-mediated correction of methylmalonyl-CoA mutase deficiency in murine fibroblasts and human hepatocytes

<p>Abstract</p> <p>Background</p> <p>Methylmalonic acidemia (MMA), a common organic aciduria, is caused by deficiency of the mitochondrial localized, 5'deoxyadenosylcobalamin dependent enzyme, methylmalonyl-CoA mutase (MUT). Liver transplantation in the absence of...

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Main Authors: Korson Mark (Author), Sloan Jennifer (Author), Dorko Kenneth (Author), Tsai Matthew S (Author), Chandler Randy J (Author), Freeman Richard (Author), Strom Stephen (Author), Venditti Charles P (Author)
Format: Book
Published: BMC, 2007-04-01T00:00:00Z.
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