Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Tear Production in a Mouse Model of Sjögren's Syndrome

• Main Authors: Hema S. Aluri (Author), Mahta Samizadeh (Author), Maria C. Edman (Author), Dillon R. Hawley (Author), Helene L. Armaos (Author), Srikanth R. Janga (Author), Zhen Meng (Author), Victor G. Sendra (Author), Pedram Hamrah (Author), Claire L. Kublin (Author), Sarah F. Hamm-Alvarez (Author), Driss Zoukhri (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of the present study was to test the potential of mouse bone marrow-derived mesenchymal stem cells (BD-MSCs) in improving tear production in a mouse model of Sjögren's syndrome dry eye and to investigate the underlying mechanisms involved. NOD mice (n=20) were randomized to receive...