Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion

• Main Authors: Pedro Henrique Bürgel (Author), Clara Luna Marina (Author), Pedro H. V. Saavedra (Author), Patrícia Albuquerque (Author), Stephan Alberto Machado de Oliveira (Author), Paulo Henrique de Holanda Veloso Janior (Author), Raffael Araújo de Castro (Author), Heino M. Heyman (Author), Carolina Coelho (Author), Radames J. B. Cordero (Author), Arturo Casadevall (Author), Joshua D. Nosanchuk (Author), Ernesto S. Nakayasu (Author), Robin C. May (Author), Aldo Henrique Tavares (Author), Anamelia Lorenzetti Bocca (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cryptococcus neoformans is an encapsulated yeast that causes disease mainly in immunosuppressed hosts. It is considered a facultative intracellular pathogen because of its capacity to survive and replicate inside phagocytes, especially macrophages. This ability is heavily dependent on various virule...