Solubility enhancement of benfotiamine, a lipid derivative of thiamine by solid dispersion technique
The present study was aimed to increase the solubility of the poorly water soluble drug benfotiamine using hydrophilic polymers (PVP K-30 and HPMC E4). Solid dispersions were prepared by kneading method. Phase solubility study, in-vitro dissolution of pure drug, physical mixtures and solid dispersio...
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| Auteurs principaux: | , , |
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| Format: | Livre |
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Wolters Kluwer Medknow Publications,
2012-01-01T00:00:00Z.
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A1234.567 |
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| Exemplaire 1 | Disponible |