Solubility enhancement of benfotiamine, a lipid derivative of thiamine by solid dispersion technique

The present study was aimed to increase the solubility of the poorly water soluble drug benfotiamine using hydrophilic polymers (PVP K-30 and HPMC E4). Solid dispersions were prepared by kneading method. Phase solubility study, in-vitro dissolution of pure drug, physical mixtures and solid dispersio...

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Main Authors: S M Patel (Author), R P Patel (Author), B G Prajapati (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
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3rd Floor Main Library

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