Association between the peripartum maternal and fetal telomere lengths and mitochondrial DNA copy numbers and preeclampsia: a prospective case-control study

• Главные авторы: Ruyi Zhang (Автор), Jiangbo Du (Автор), Zhendong Xiao (Автор), Yuan Jiang (Автор), Liang Jin (Автор), Qiao Weng (Автор)
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• Опубликовано: BMC, 2022-06-01T00:00:00Z.
• Предметы: article
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Abstract Purpose To explore changes in telomere length (TL) and mitochondrial copy number (mtDNA-CN) in preeclampsia (PE) and to evaluate the combined effect of maternal TL and mtDNA-CN on PE risk. Methods A case-control study of 471 subjects (130 PE cases and 341 age frequency matched controls with...