Nalmefene vs. dexmedetomidine for prevention of postoperative hyperalgesia in patients undergoing laparoscopic gynecological surgery with remifentanil infusion: A randomized double-blind controlled trial

• Auteurs principaux: Zhen Jia (Auteur), Yi Chen (Auteur), Tianyu Gao (Auteur), Yuan Yuan (Auteur), Yuxin Zheng (Auteur), Yegong Xie (Auteur), Guolin Wang (Auteur), Yonghao Yu (Auteur), Linlin Zhang (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Intraoperative remifentanil infusion may paradoxically induce post-surgical hyperalgesia. Dexmedetomidine reportedly reduces opioid-induced hyperalgesia. Nalmefene selectively reverses several side-effects of opioids without impairing analgesia. Herein, this randomized, double-blind controlled trial...