Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway

• Главные авторы: Maho Morimatsu (Автор), Erika Yamashita (Автор), Shigeto Seno (Автор), Takao Sudo (Автор), Junichi Kikuta (Автор), Hiroki Mizuno (Автор), Daisuke Okuzaki (Автор), Daisuke Motooka (Автор), Masaru Ishii (Автор)
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• Опубликовано: BMC, 2020-07-01T00:00:00Z.
• Предметы: article
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Abstract Background Dormant chemotherapy-resistant leukemia cells can survive for an extended period before relapse. Nevertheless, the mechanisms underlying the development of chemoresistance in vivo remain unclear. Methods Using intravital bone imaging, we characterized the behavior of murine acute...