Migration arrest of chemoresistant leukemia cells mediated by MRTF-SRF pathway

• Main Authors: Maho Morimatsu (Author), Erika Yamashita (Author), Shigeto Seno (Author), Takao Sudo (Author), Junichi Kikuta (Author), Hiroki Mizuno (Author), Daisuke Okuzaki (Author), Daisuke Motooka (Author), Masaru Ishii (Author)
• Format: Book
• Published: BMC, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Dormant chemotherapy-resistant leukemia cells can survive for an extended period before relapse. Nevertheless, the mechanisms underlying the development of chemoresistance in vivo remain unclear. Methods Using intravital bone imaging, we characterized the behavior of murine acute...