Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Mesenchymal stem cell-originated exosomal circDIDO1 suppresses hepatic stellate cell activation by miR-141-3p/PTEN/AKT pathway in human liver fibrosis

Liver fibrosis is a common pathologic stage of the development of liver failure. It has showed that exosomes loaded with therapeutic circRNAs can be manufactured in bulk by exosome secreted cells in vitro, thus enabling personalized treatment. This study aimed to investigate the role of exosome-base...

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Main Authors: Li Ma (Author), Junfeng Wei (Author), Yanli Zeng (Author), Junping Liu (Author), Erhui Xiao (Author), Yuehua Kang (Author), Yi Kang (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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