The effect of ERCC1 and ERCC2 gene polymorphysims on response to cisplatin based therapy in osteosarcoma patients

Abstract Background Cisplatin is one of the major drugs that used in the treatment of osteosarcoma. Cisplatin exerts its function by making cisplatin-DNA adducts culminating in cellular death. These adducts found to be repaired by nucleotide excision repair (NER) pathway. This study aimed to evaluat...

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Main Authors: Hadeel Obiedat (Author), Nasr Alrabadi (Author), Eyad Sultan (Author), Marwa Al Shatti (Author), Malek Zihlif (Author)
Format: Book
Published: BMC, 2018-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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