Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

• Главные авторы: Stine Normann Hansen (Автор), Anne Marie V. Schou-Pedersen (Автор), Jens Lykkesfeldt (Автор), Pernille Tveden-Nyborg (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2018-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Vitamin C (vitC) is important in the developing brain, acting both as an essential antioxidant and as co-factor in the synthesis and metabolism of monoaminergic neurotransmitters. In guinea pigs, vitC deficiency results in increased oxidative stress, reduced hippocampal volume and neuronal numbers,...