Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

• Main Authors: Stine Normann Hansen (Author), Anne Marie V. Schou-Pedersen (Author), Jens Lykkesfeldt (Author), Pernille Tveden-Nyborg (Author)
• Format: Bog
• Udgivet: MDPI AG, 2018-06-01T00:00:00Z.
• Fag: article
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Vitamin C (vitC) is important in the developing brain, acting both as an essential antioxidant and as co-factor in the synthesis and metabolism of monoaminergic neurotransmitters. In guinea pigs, vitC deficiency results in increased oxidative stress, reduced hippocampal volume and neuronal numbers,...