Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair

• मुख्य लेखकों: Man Xiao (लेखक), Jing Cai (लेखक), Liqiong Cai (लेखक), Jinghui Jia (लेखक), Lisha Xie (लेखक), Ying Zhu (लेखक), Bangxing Huang (लेखक), Dongdong Jin (लेखक), Zehua Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2017-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Resistance to platinum-based chemotherapy remains a great challenge for ovarian cancer treatment. The human let-7 family contains 13 members located on nine different chromosomes, and most members have been implicated in the modulation of drug sensitivity in cancers. Our previous...