Coadministration of fluconazole to boost subtherapeutic sirolimus concentrations: A case report

• Asıl Yazarlar: Camilo Scherkl (Yazar), Andreas D. Meid (Yazar), Sven E. Cuntz (Yazar), Laura Classen (Yazar), Johanna Weiss (Yazar), David Czock (Yazar), Walter E. Haefeli (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2024-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Individual sirolimus whole blood concentrations are highly variable, critically influenced by the concomitant use of cytochrome P450 (CYP) 3A inducers or inhibitors, and also modulated by food. Therapeutic drug monitoring is therefore recommended, especially at treatment start or in circums...