Realgar transforming solution as a novel arsenic agent with a lower risk of cardiotoxicity

• Main Authors: Yang Hai (Author), Peng Song (Author), Xin Wang (Author), Longhe Zhao (Author), Qinjian Xie (Author), Jianyin Li (Author), Yang Li (Author), Hongyu Li (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

QTc prolongation has been observed during arsenic trioxide and realgar's clinical use, and become a huge obstacle for the application. Our lab has obtained the soluble arsenic from realgar named realgar transforming solution or RTS. In this study, we first evaluated the cytotoxicity on NB4 cell...