Improvement of Erdheim-Chester disease-related renal failure after treatment with anakinra
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by infiltrates of lipid-laden CD68+/CD1a− histiocytes, affecting heart, lungs, central nervous system, and bones. Kidney and adjacent structures can also be affected, leading to renal failure in about 30% of case...
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| Format: | Book |
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The Korean Society of Nephrology,
2014-09-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_29b72fc33d734ce38e080f19cbc834a6 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Manuel Alfredo Podestà |e author |
| 700 | 1 | 0 | |a Giorgio Graziani |e author |
| 700 | 1 | 0 | |a Francesco Reggiani |e author |
| 700 | 1 | 0 | |a Michele Buemi |e author |
| 700 | 1 | 0 | |a Salvatore Badalamenti |e author |
| 700 | 1 | 0 | |a Claudio Ponticelli |e author |
| 245 | 0 | 0 | |a Improvement of Erdheim-Chester disease-related renal failure after treatment with anakinra |
| 260 | |b The Korean Society of Nephrology, |c 2014-09-01T00:00:00Z. | ||
| 500 | |a 2211-9132 | ||
| 500 | |a 10.1016/j.krcp.2014.07.007 | ||
| 520 | |a Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by infiltrates of lipid-laden CD68+/CD1a− histiocytes, affecting heart, lungs, central nervous system, and bones. Kidney and adjacent structures can also be affected, leading to renal failure in about 30% of cases. The diagnosis is challenging, and treatment is generally based on administration of interferon-alpha (IFNα), but preliminary results also showed the therapeutic efficacy of anakinra, an antagonist of the receptor of interleukin-1 (IL-1). We report the case of an elderly patient with ECD and severe involvement of the heart and kidneys who was successfully treated with anakinra. | ||
| 546 | |a EN | ||
| 546 | |a KO | ||
| 690 | |a Anakinra | ||
| 690 | |a Erdheim-Chester disease | ||
| 690 | |a Renal failure | ||
| 690 | |a Internal medicine | ||
| 690 | |a RC31-1245 | ||
| 690 | |a Specialties of internal medicine | ||
| 690 | |a RC581-951 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Kidney Research and Clinical Practice, Vol 33, Iss 3, Pp 165-167 (2014) | |
| 787 | 0 | |n http://www.sciencedirect.com/science/article/pii/S2211913214000874 | |
| 787 | 0 | |n https://doaj.org/toc/2211-9132 | |
| 856 | 4 | 1 | |u https://doaj.org/article/29b72fc33d734ce38e080f19cbc834a6 |z Connect to this object online. |