Translating bacteriophage-derived depolymerases into antibacterial therapeutics: Challenges and prospects

• Main Authors: Honglan Wang (Author), Yannan Liu (Author), Changqing Bai (Author), Sharon Shui Yee Leung (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Predatory bacteriophages have evolved a vast array of depolymerases for bacteria capture and deprotection. These depolymerases are enzymes responsible for degrading diverse bacterial surface carbohydrates. They are exploited as antibiofilm agents and antimicrobial adjuvants while rarely inducing bac...