In Vitro ADME, Preclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of RBx14255, a Novel Ketolide with Pharmacodynamics Against Multidrug-Resistant Bacterial Pathogens

Purpose: The preclinical pharmacokinetic and pharmacodynamic properties of a potent fluoroketolide RBx14255 against Streptococcus pneumoniae and Haemophilus influenzae was compared with telithromycin and human clinical dose was predicted for preclinical development. Methods: The in vitro pharmacokin...

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Main Authors: Trdib Chaira (Author), Tarani Barman (Author), VETHAKKANI SAMUEL RAJ (Author)
Format: Book
Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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