Apoptotic cell death, detected ex vivo in peripheral blood lymphocytes of HIV-1 infected persons

• Main Authors: L. F. te Velde (Author), I. Vermes (Author), C. Haanen (Author), C. P. M. Reutelingsperger (Author), C. H. H. ten Napel (Author)
• Format: Book
• Published: Hindawi Limited, 1996-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In HIV-1 infection the ongoing depletion of CD4+ T-lymphocytes is believed, to a large extent, to be due to apoptosis. Until now quantitative information about in vivo apoptosis of lymphocytes in HIV-patients is scarce because of the very nature of the apoptotic process. Successful detection of apop...