Targeted Antitumor Mechanism of C-PC/CMC-CD55sp Nanospheres in HeLa Cervical Cancer Cells

• Main Authors: Guoxiang Liu (Author), Xiaohui Xu (Author), Liangqian Jiang (Author), Huanhuan Ji (Author), Feng Zhu (Author), Bingnan Jin (Author), Jingjing Han (Author), Xiaolei Dong (Author), Fanghao Yang (Author), Bing Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In vitro studies had shown that C-Phycocyanin (C-PC) inhibited cervical cancer HeLa cells growth. We constructed C-PC/CMC-CD55sp nanospheres using C-PC, Carboxymethyl Chitosan (CMC), and CD55 ligand peptide (CD55sp) to allow for targeted antitumor effects against HeLa cells in vitro and in vivo. The...