Extracellular vesicles from Leishmania-infected macrophages confer an anti-infection cytokine-production profile to naïve macrophages.

• Main Authors: André Cronemberger-Andrade (Author), Luciana Aragão-França (Author), Cintia Figueiredo de Araujo (Author), Viviane Junqueira Rocha (Author), Mariana da Cruz Borges-Silva (Author), Cláudio P Figueira (Author), Pablo R Oliveira (Author), Luiz A R de Freitas (Author), Patrícia S T Veras (Author), Lain Pontes- (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Extracellular vesicles (EVs) are structures with phospholipid bilayer membranes and 100-1000 nm diameters. These vesicles are released from cells upon activation of surface receptors and/or apoptosis. The production of EVs by dendritic cells, mast cells, macrophages, and B and T lymphocyt...