Glycoform-resolved FcɣRIIIa affinity chromatography-mass spectrometry

Glycoform-resolved FcɣRIIIa affinity chromatography-mass spectrometry

Determination of the impact of individual antibody glycoforms on FcɣRIIIa affinity, and consequently antibody-dependent cell-mediated cytotoxicity (ADCC) previously required high purity glycoengineering. We hyphenated FcɣRIIIa affinity chromatography to mass spectrometry, which allowed direct affini...

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Main Authors: Steffen Lippold (Author), Simone Nicolardi (Author), Elena Domínguez-Vega (Author), Anna-Katharina Heidenreich (Author), Gestur Vidarsson (Author), Dietmar Reusch (Author), Markus Haberger (Author), Manfred Wuhrer (Author), David Falck (Author)
Format: Book
Published: Taylor & Francis Group, 2019-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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