Mdivi-1 Protects CD4+ T Cells against Apoptosis via Balancing Mitochondrial Fusion-Fission and Preventing the Induction of Endoplasmic Reticulum Stress in Sepsis

• Hauptverfasser: You Wu (Verfasst von), Yong-Ming Yao (Verfasst von), He-Liang Ke (Verfasst von), Lan Ying (Verfasst von), Yao Wu (Verfasst von), Guang-Ju Zhao (Verfasst von), Zhong-Qiu Lu (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2019-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Apoptosis of CD4+ T cells plays a central role in the progression of sepsis because it is associated with subsequent immunosuppression and the lack of specific treatment. Thus, developing therapeutic strategies to attenuate the apoptosis of CD4+ T cells in sepsis is critical. Several studies have de...