Discovery of Leishmania Druggable Serine Proteases by Activity-Based Protein Profiling

• Auteurs principaux: Exequiel O. J. Porta (Auteur), Jaime A. Isern (Auteur), Karunakaran Kalesh (Auteur), Patrick G. Steel (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Leishmaniasis are a group of diseases caused by parasitic protozoa of the genus Leishmania. Current treatments are limited by difficult administration, high cost, poor efficacy, toxicity, and growing resistance. New agents, with new mechanisms of action, are urgently needed to treat the disease. Alt...