Genetic Signatures From RNA Sequencing of Pediatric Localized Scleroderma Skin

• Main Authors: Emily Mirizio (Author), Christopher Liu (Author), Qi Yan (Author), Julia Waltermire (Author), Roosha Mandel (Author), Kaila L. Schollaert (Author), Liza Konnikova (Author), Xinjun Wang (Author), Wei Chen (Author), Kathryn S. Torok (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to explore the skin transcriptional profile in pediatric localized scleroderma (LS) to provide a better understanding of the altered immune and fibrotic pathways promoting disease. LS is a progressive disease of the skin and underlying tissue that causes significant fun...