Pan-cancer analysis identifies NT5E as a novel prognostic biomarker on cancer-associated fibroblasts associated with unique tumor microenvironment

• Main Authors: Xin-miao Xue (Author), Yu-yang Liu (Author), Xue-min Chen (Author), Bing-yan Tao (Author), Peng Liu (Author), Han-wen Zhou (Author), Chi Zhang (Author), Li Wang (Author), Yu-ke Jiang (Author), Zhi-wei Ding (Author), Wei-dong Shen (Author), Jun Zhang (Author), Shi-ming Yang (Author), Fang-yuan Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Ecto-5'-nucleotidase (NT5E) encodes the cluster of differentiation 73 (CD73), whose overexpression contributes to the formation of immunosuppressive tumor microenvironment and is related to exacerbated prognosis, increased risk of metastasis and resistance to immunotherapy of variou...