Prevalence and clinical phenotype of the triplicated α-globin genes and its ethnic and geographical distribution in Guizhou of China

• Glavni autori: Xi Luo (Autor), Xiang-mei Zhang (Autor), Liu-song Wu (Autor), Jindong Chen (Autor), Yan Chen (Autor)
• Format: Knjiga
• Izdano: BMC, 2021-04-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Background α-thalassemia is relatively endemic in Guizhou province of southwestern China. To predict the clinical manifestations of α-globin gene aberration for genetic counseling, we examined the prevalence of the α-globin triplication and the genotype-phenotype correlation in this subpopu...