Prevalence and clinical phenotype of the triplicated α-globin genes and its ethnic and geographical distribution in Guizhou of China

Abstract Background α-thalassemia is relatively endemic in Guizhou province of southwestern China. To predict the clinical manifestations of α-globin gene aberration for genetic counseling, we examined the prevalence of the α-globin triplication and the genotype-phenotype correlation in this subpopu...

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Bibliografski detalji
Glavni autori: Xi Luo (Autor), Xiang-mei Zhang (Autor), Liu-song Wu (Autor), Jindong Chen (Autor), Yan Chen (Autor)
Format: Knjiga
Izdano: BMC, 2021-04-01T00:00:00Z.
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