Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines

• Main Authors: Filipe N. Franco (Author), Júlia T. Oliveira (Author), Kimberly B. Tecchio (Author), Flaviana A. Santos (Author), Moacyr J.B.M. Rêgo (Author), Francisco J.B. Mendonça-Júnior (Author), Maira G.R. Pitta (Author), Michelly C. Pereira (Author), Rosy I.M.A. Ribeiro (Author), Vanessa J.S.V. Santos (Author), Fabio V. Santos (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell lines. The aim of the present study was to evalu...